15-16th January 2009, Thon Hotel, Ski, Norway

Introduction

Recordings of extracellular potentials have been, and still are, essential for understanding the living brain. The high-frequency part of the signal, the multi-unit activity (MUA), mainly reflects firing of action potentials in the vicinity of the electrode. The low-frequency part, the local-field potential (LFP), appears to reflect subthreshold activity from a larger group of surrounding neurons.


Despite their long history in neuroscience the meaning of these extracellular potentials are still not fully understood. What can the LFP tell us about the underlying activity in neurons and neuronal networks? Which neurons dominate the MUA? These and similar questions need to be answered for us to take full advantage of the host of new types of multielectrodes with new geometries and ever more electrode contacts. Further, a better understanding of these issues will likely also be important for the development of good 'brain-machine interfaces'.


In the last few years a growing number of researchers are getting interested in these issues, and this workshop will bring together many of them. A main theme of the workshop will be the development and application of new mathematical and data analysis techniques to extract more information from multielectrode extracellular data.

Organized by Gaute T. Einevoll (Norwegian University of Life Sciences)

and Daniel K. Wójcik (Nencki Institute of Experimental Biology)


Supported by a grant from Norway through the Norwegian Financial Mechanism and the Polish-Norwegian Research Fund